Article
Gene array analysis of the effects of chronic adrenocorticotropic hormone in vivo on immature rat adrenal glands.
The Journal of steroid biochemistry and molecular biology - 1 Jun 2005
Lee Julie J, Widmaier Eric P
Abstract excerpt
Development of a mature adrenocortical phenotype is a critical event in the transition of mammals from fetal to postnatal life. We previously reported that the functional maturation of the adrenal glands of newborn rats is accelerated by adrenocorticotropic hormone (ACTH). We report here that chronic exposure of neonatal/juvenile rat pups to ACTH in vivo results in significant changes in expression of over 200...
Topics
- Adrenal Glands
- Adrenocorticotropic Hormone
- Aging
- Animals
- DNA Primers
- Female
- Gene Expression Regulation, Developmental
- Male
- Oligonucleotide Array Sequence Analysis
- Phenotype
- Polymerase Chain Reaction
