Article
Characterization of a divergent glycosomal microbody phosphoglycerate kinase from Trypanosoma brucei.
Molecular and biochemical parasitology - 1 Aug 1993
Alexander K, Parsons M
Abstract excerpt
There are 3 loci in the phosphoglycerate kinase (PGK) gene complex of Trypanosoma brucei. The PGK-A gene product, which we term 56PGK, is targeted to glycosomal microbodies and is highly homologous to the parasite's 2 known PGKs (one cytoplasmic and one glycosomal). However, 56PGK contains an 80 amino acid insertion as well as numerous substitutions compared to the other PGKs. The complementation and kinetic...
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