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Article

Characterization of a divergent glycosomal microbody phosphoglycerate kinase from Trypanosoma brucei.

Molecular and biochemical parasitology - 1 Aug 1993

Alexander K, Parsons M

Abstract excerpt

There are 3 loci in the phosphoglycerate kinase (PGK) gene complex of Trypanosoma brucei. The PGK-A gene product, which we term 56PGK, is targeted to glycosomal microbodies and is highly homologous to the parasite's 2 known PGKs (one cytoplasmic and one glycosomal). However, 56PGK contains an 80 amino acid insertion as well as numerous substitutions compared to the other PGKs. The complementation and kinetic...

Topics

Amino Acid Sequence
Animals
Escherichia coli
Gene Expression
Genes, Protozoan
Genetic Complementation Test
Kinetics
Microbodies
Molecular Sequence Data
Phenotype
Phosphoglycerate Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombinant Fusion Proteins

Trypanosoma brucei brucei

Source

Identifiers

PMID: 8232417
DOI: 10.1016/0166-6851(93)90137-m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8232417-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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