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Article

Molecular cloning and analysis of two tandemly linked genes for pyruvate kinase of Trypanosoma brucei.

European journal of biochemistry - 15 Aug 1991

Allert S, Ernest I, Poliszczak A, Opperdoes F R, Michels P A

Abstract excerpt

In Trypanosoma brucei (stock 427) genes encoding the glycolytic enzyme pyruvate kinase are present on two homologous chromosomes. We have cloned and characterized one of the alleles. Two large, tandemly arranged open reading frames were found, each coding for a pyruvate kinase polypeptide of 498 amino acids. The gene sequences differ at 15 positions, resulting in five amino acid substitutions. The calculated...

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PMID: 1879424
DOI: 10.1111/j.1432-1033.1991.tb21043.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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