The role of nucleotides conserved in eukaryotic initiator methionine tRNAs in initiation of protein synthesis.

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Article

The role of nucleotides conserved in eukaryotic initiator methionine tRNAs in initiation of protein synthesis.

The Journal of biological chemistry - 25 Nov 1993

Drabkin H J, Helk B, RajBhandary U L

Abstract excerpt

Mutant human initiator tRNA genes carrying changes in each of the three features unique to eukaryotic initiator tRNAs have been constructed, and introduced into CV-1 monkey kidney cells using SV40 virus vectors. The mutant tRNA genes are expressed, and the mutant tRNAs can all be aminoacylated wi...

Topics

Acylation
Animals
Base Sequence
Cell-Free System
Cells, Cultured
Conserved Sequence
Haplorhini
Humans
Methionine-tRNA Ligase
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Nucleotides
Protein Biosynthesis
RNA, Transfer, Met
Rabbits

Source

Open in PubMed

Identifiers

PMID: 8227087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8227087-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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