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Article

The role of nucleotides conserved in eukaryotic initiator methionine tRNAs in initiation of protein synthesis.

The Journal of biological chemistry - 25 Nov 1993

Drabkin H J, Helk B, RajBhandary U L

Abstract excerpt

Mutant human initiator tRNA genes carrying changes in each of the three features unique to eukaryotic initiator tRNAs have been constructed, and introduced into CV-1 monkey kidney cells using SV40 virus vectors. The mutant tRNA genes are expressed, and the mutant tRNAs can all be aminoacylated with both rabbit liver and Escherichia coli methionyl-tRNA synthetases. Based on aminoacylation levels, the tRNAs are...

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PMID: 8227087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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