Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complementation of bacteriophage lambda integrase mutants: evidence for an intersubunit active site.

The EMBO journal - 1 Dec 1993

Han Y W, Gumport R I, Gardner J F

Abstract excerpt

Site-specific recombination of bacteriophage lambda starts with the formation of higher-order protein--DNA complexes, called 'intasomes', and is followed by a series of steps, including the initial DNA cleavage, top-strand exchange, branch migration and bottom-strand exchange, to produce recombinant products. One of the intasomes formed during excisive recombination (the attL complex) is composed of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cloning, Molecular
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Complementation Test

Share to Kinetics

Share to Mutagenesis

Share to Mutation

Share to Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 8223467
DOI: 10.1002/j.1460-2075.1993.tb06146.x
PMCID: PMC413888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complementation of bacteriophage lambda integrase mutants: evidence for an intersubunit active site.PMID 8223467Read ↗

Gamma integrase complementation at the level of DNA binding and complex formation.Semantic proximity Read ↗

Regulation of site-specific recombination by the C-terminus of lambda integrase.Semantic proximity Read ↗

Attenuating functions of the C terminus of lambda integrase.Semantic proximity Read ↗

The efficiency of mispaired ligations by lambda integrase is extremely sensitive to context.Semantic proximity Read ↗

Identifying determinants of recombination specificity: construction and characterization of chimeric bacteriophage integrases.Semantic proximity Read ↗

Mechanism of cleavage and ligation by FLP recombinase: classification of mutations in FLP protein by in vitro complementation analysis.Semantic proximity Read ↗

Complementation between HIV integrase proteins mutated in different domains.Semantic proximity Read ↗

Mutations at residues 282, 286, and 293 of phage lambda integrase exert pathway-specific effects on synapsis and catalysis in recombination.Semantic proximity Read ↗

Mutational analysis of protein binding sites involved in formation of the bacteriophage lambda attL complex.Semantic proximity Read ↗

Disruption of a salt bridge dramatically accelerates subunit exchange in duck delta2 crystallin.Semantic proximity Read ↗

Non-equivalent interactions between amino-terminal domains of neighboring lambda integrase protomers direct Holliday junction resolution.Semantic proximity Read ↗

Genetic analysis of second-site revertants of bacteriophage lambda integrase mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.