Article
Models of neoplasia and their diagnostic implications: a historical perspective.
Clinical chemistry - 1 Nov 1993
Goldberg D M, Diamandis E P
Abstract excerpt
In comparison with normal cells, cancer cells have an enhanced ability to trap both nitrogen and energy; an enhanced operation of the glycolytic and direct oxidative pathways, leading to accumulation of lactate and increased production of NADPH; and a greater content of lysosomal hydrolases. Thes...
Topics
- History, 20th Century
- Humans
- Models, Biological
- Neoplasm Metastasis
- Neoplasms
- Phenotype
