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Article

How aneuploidy affects metabolic control and causes cancer.

The Biochemical journal - 15 Jun 1999

Rasnick D, Duesberg P H

Abstract excerpt

The complexity and diversity of cancer-specific phenotypes, including de-differentiation, invasiveness, metastasis, abnormal morphology and metabolism, genetic instability and progression to malignancy, have so far eluded explanation by a simple, coherent hypothesis. However, an adaptation of Metabolic Control Analysis supports the 100-year-old hypothesis that aneuploidy, an abnormal number of chromosomes, is the...

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Identifiers

PMID: 10359645
PMCID: PMC1220292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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