Article
Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.
Cancer research - 1 Nov 1993
Han H J, Yanagisawa A, Kato Y, Park J G, Nakamura Y
Abstract excerpt
To examine genetic instability during carcinogenesis, we screened 171 carcinomas of the breast, liver, proximal colon, stomach, pancreas, uterine cervix, and ovary for replication error at four microsatellite marker loci on chromosome 2, 3, and 17. A significantly high incidence of genetic instability was observed in pancreatic (6 of 9 tumors) and gastric cancers (22 of 57 cases). In other types of carcinoma, the...
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