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Article

SV40 large T antigen functions at two distinct steps in virion assembly.

Virology - 1 Oct 1994

Spence S L, Pipas J M

Abstract excerpt

The SV40 large T antigen mutant 5002 has two amino acid substitutions (L19-F; P28-S) and is defective for productive viral infection as demonstrated by its small plaques that arise very late and by a 100-fold reduced yield of infectious progeny. 5002 replicates viral DNA at the same time postinfection as wild-type SV40, and the production of progeny DNA molecules is only marginally reduced. Furthermore, the viral...

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Source

Identifiers

PMID: 8091652
DOI: 10.1006/viro.1994.1524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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