No evidence for genomic imprinting of the human BCR gene.

Article

No evidence for genomic imprinting of the human BCR gene.

Blood - 15 Jun 1994

Fioretos T, Heisterkamp N, Groffen J

Abstract excerpt

Chronic myeloid leukemias and 5% to 20% of acute lymphoid leukemias are characterized by the Philadelphia chromosome, a reciprocal chromosomal translocation, t(9;22)(q34;q11), generating BCR-ABL and ABL-BCR fusion genes. Cytogenetic studies have recently shown a preferential involvement of the pa...

Topics

Alleles
Base Sequence
Fusion Proteins, bcr-abl
Gene Expression
Humans
Molecular Sequence Data
Oncogene Proteins
Oncogenes
Polymerase Chain Reaction
Polymorphism, Genetic
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcr

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