Standpoint on imprinting of BCR and ABL.

Article

Standpoint on imprinting of BCR and ABL.

Leukemia - 1 Apr 1995

Fioretos T, Heisterkamp N, Groffen J

Abstract excerpt

Cytogenetic studies of Ph-positive leukemic patients and their parents have indicated that chromosome 22 involved in the formation of the t(9;22) is of maternal origin, whereas chromosome 9 is preferentially of paternal origin. These data have suggested that the two genes BCR and ABL, which become fused through the translocation, might be imprinted, ie expressed in a parental-specific manner. Recent molecular...

Topics

Alleles
Genes, abl
Humans
Imprinting, Psychological
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Philadelphia Chromosome
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcr
Translocation, Genetic

Source

Open in PubMed

Identifiers

PMID: 7723414

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7723414-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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