Article
Pokeweed antiviral protein (PAP) mutations which permit E.coli growth do not eliminate catalytic activity towards prokaryotic ribosomes.
Nucleic acids research - 11 May 1994
Chaddock J A, Lord J M, Hartley M R, Roberts L M
Abstract excerpt
Pokeweed antiviral protein (PAP) has N-glycosidase activity towards both eukaryotic and prokaryotic ribosomes. This is in marked contrast with the A chains of type 2 ribosome inactivating proteins (RIPs) such as ricin and abrin, which inactivate only eukaryotic ribosomes. A recent report describe...
Topics
- Base Sequence
- Catalysis
- Cloning, Molecular
- DNA
- Escherichia coli
- Glycoside Hydrolases
- Molecular Sequence Data
- Mutation
- N-Glycosyl Hydrolases
- Plant Proteins
- Plants
- Ribosome Inactivating Proteins, Type 1
- Ribosomes