Article
A non-toxic pokeweed antiviral protein mutant inhibits pathogen infection via a novel salicylic acid-independent pathway.
Plant molecular biology - 1 Sept 2000
Zoubenko O, Hudak K, Tumer N E
Abstract excerpt
Pokeweed antiviral protein (PAP), a ribosome-inactivating protein isolated from Phytolacca americana, is characterized by its ability to depurinate the sarcin/ricin (S/R) loop of the large rRNA of prokaryotic and eukaryotic ribosomes. In this study, we present evidence that PAP is associated with ribosomes and depurinates tobacco ribosomes in vivo by removing more than one adenine and a guanine. A mutant of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
