Article
Pokeweed antiviral protein inhibits brome mosaic virus replication in plant cells.
The Journal of biological chemistry - 20 May 2005
Picard Daniel, Kao C Cheng, Hudak Katalin A
Abstract excerpt
Pokeweed antiviral protein (PAP) is a ribosome-inactivating protein isolated from the pokeweed plant (Phytolacca americana) that inhibits the proliferation of several plant and animal viruses. We have shown previously that PAP and nontoxic mutants of PAP can directly depurinate brome mosaic virus (BMV) RNA in vitro, resulting in reduced viral protein translation. Here we expand on these initial studies and, using...
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