Article
Dominant mutants identify new roles for p34cdc2 in mitosis.
The EMBO journal - 15 May 1995
Labib K, Craven R A, Crawford K, Nurse P
Abstract excerpt
A large number of dominant mutants have been generated in the fission yeast cdc2 gene, causing lethality when expressed in wild-type cells. The mutants interfere with distinct aspects of p34cdc2 function, producing one of four different phenotypes: mitotic arrest, multiple rounds of S phase in the absence of mitosis, premature mitosis or G2 arrest. The mitotic mutants DL41, DL45 and DL50 are characterized in this...
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