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Article

Mutational analysis of Saccharomyces cerevisiae ARF1.

The Journal of biological chemistry - 6 Jan 1995

Kahn R A, Clark J, Rulka C, Stearns T, Zhang C J, Randazzo P A, Terui T, Cavenagh M

Abstract excerpt

Wild type and eight point mutants of Saccharomyces cerevisiae ARF1 were expressed in yeast and bacteria to determine the roles of specific residues in in vivo and in vitro activities. Mutations at either Gly2 or Asp26 resulted in recessive loss of function. It was concluded that N-myristoylation is required for Arf action in cells but not for either nucleotide exchange or cofactor activities in vitro. Asp26...

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Source

Identifiers

PMID: 7814365
DOI: 10.1074/jbc.270.1.143

Genes

ARF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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