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Article

Breakthrough infections and identification of a viral variant in Gambian children immunized with hepatitis B vaccine.

The Journal of infectious diseases - 1 Jun 1994

Fortuin M, Karthigesu V, Allison L, Howard C, Hoare S, Mendy M, Whittle H C

Abstract excerpt

Hepatitis B (HB) breakthrough infections, identified by the presence of HB core (c) antibody, were found in 32 of 358 Gambian children vaccinated with plasma-derived HB vaccine. Over 2 years, 15 of these children lost their HBc antibodies. These children had significantly higher HB surface antibody levels before infection than those who retained HBc antibodies. One child, who responded well to the vaccine, had HB...

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Source

Identifiers

PMID: 8195620
DOI: 10.1093/infdis/169.6.1374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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