Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Breakthrough infections and identification of a viral variant in Gambian children immunized with hepatitis B vaccine.

The Journal of infectious diseases - 1 Jun 1994

Fortuin M, Karthigesu V, Allison L, Howard C, Hoare S, Mendy M, Whittle H C

Abstract excerpt

Hepatitis B (HB) breakthrough infections, identified by the presence of HB core (c) antibody, were found in 32 of 358 Gambian children vaccinated with plasma-derived HB vaccine. Over 2 years, 15 of these children lost their HBc antibodies. These children had significantly higher HB surface antibo...

Topics

Child
Gambia
Genetic Variation
Hepatitis B
Hepatitis B Antibodies
Hepatitis B Vaccines
Hepatitis B virus
Humans
Vaccination

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8195620
DOI: 10.1093/infdis/169.6.1374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8195620-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Breakthrough infections and identification of a viral variant in Gambian children immunized with hepatitis B vaccine.PMID 8195620Read ↗

Hepatitis B virus vaccine breakthrough infection: surveillance of S gene mutants of HBV.Semantic proximity Read ↗

A hepatitis B virus variant found in the sera of immunised children induces a conformational change in the HBsAg "a" determinant.Semantic proximity Read ↗

Acute hepatitis B infection escaping vaccination: A case report.Semantic proximity Read ↗

Acute hepatitis B caused by a vaccine-escape HBV strain in vaccinated subject: sequence analysis and therapeutic strategy.Semantic proximity Read ↗

Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus.Semantic proximity Read ↗

Vaccine-induced escape mutant of hepatitis B virus.Semantic proximity Read ↗

Characterization of a breakthrough vaccine escape strain associated with overt hepatitis B virus infection.Semantic proximity Read ↗

Association between an MHC class II allele and clearance of hepatitis B virus in the Gambia.Semantic proximity Read ↗

Breakthrough of hepatitis B virus escape mutants after vaccination and virus reactivation.Semantic proximity Read ↗

Hepatitis B virus S gene mutants in infants infected despite immunoprophylaxis.Semantic proximity Read ↗

Infectivity and Pathogenicity in Chimpanzees of a Surface Gene Mutant of Hepatitis B Virus that Emerged in a Vaccinated InfantSemantic proximity Read ↗

Prevalence of HBV core promoter/precore/core mutations in Gambian chronic carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.