Article
Breakthrough of hepatitis B virus escape mutants after vaccination and virus reactivation.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2006
Gerlich Wolfram H
Abstract excerpt
Escape mutants of hepatitis B virus (HBV) carry mutations in the major antigenic region of the hepatitis B surface antigen (HBsAg). They are able to grow in the presence of antibodies against HBsAg (anti-HBs) and may escape detection by immuno assays for HBsAg. Antibodies against HBV core antigen (anti-HBc) are considered to be a universal marker for active or resolved HBV infections but they may appear very...
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