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Article

Acute hepatitis B infection escaping vaccination: A case report.

Medicine - 29 May 2026

Leonhard Sonja E, Fioole Daphne N, Benschop Kimberley S M, Willems Roel P J, Petrignani Mariska, Voordouw Bettie C G, Smeets Leonard C, Zaaijer Hans L

Abstract excerpt

RATIONALE: Hepatitis B virus (HBV) is an important cause of acute and chronic infectious hepatitis globally. Vaccines against HBV are widely available and generally lead to lifelong protection against chronic infection, disease, and infectivity. Vaccine failure, in which a person fails to form sufficiently high antibody titers, occurs in 5% to 10% of the population. Vaccine failure due to mutations in the virus,...

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Identifiers

PMID: 42216401
DOI: 10.1097/MD.0000000000048735
PMCID: PMC13225548

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