Hepatitis B virus S gene mutants in infants infected despite immunoprophylaxis.

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Article

Hepatitis B virus S gene mutants in infants infected despite immunoprophylaxis.

Chinese medical journal - 1 Apr 2001

Zhu Q, Lu Q, Xiong S, Yu H, Duan S

Abstract excerpt

OBJECTIVE: To assess the correlation between hepatitis B virus (HBV) surface gene mutant infection and hepatitis B (HB) vaccination failure. METHODS: Using sera from 106 infants who were born to HBV carrier mothers and failed in HB immunoprophylaxis, HBV S gene was amplified by PCR, transferred to nylon membranes for Southern blots, and then hybridized with oligonucleotide probes. Eleven of non-hybridizing...

Topics

DNA, Viral
Female
Hepatitis B
Hepatitis B Vaccines
Hepatitis B virus
Humans
Infant
Infant, Newborn
Male
Mutation
Vaccination
Viral Envelope Proteins

Source

Open in PubMed

Identifiers

PMID: 11780452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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