Article
The activation region of the Tat protein of human immunodeficiency virus type-1 functions in yeast.
Nucleic acids research - 25 Apr 1994
Subramanian T, D'Sa-Eipper C, Elangovan B, Chinnadurai G
Abstract excerpt
The N-terminal 48 amino acids of the Tat protein of human immunodeficiency virus type (HIV)-1 constitute its activation region. This region can autonomously activate transcription when targeted to the HIV-1 long terminal repeat or certain heterologous promoters either through DNA binding sites located upstream of the transcription initiation site or via downstream RNA binding sites in mammalian cells. To...
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