Evidence for functional interaction between the HIV-1 Tat transactivator and the TATA box binding protein in vivo.

doi:10.1006/jmbi.1995.0368

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Article

Evidence for functional interaction between the HIV-1 Tat transactivator and the TATA box binding protein in vivo.

Journal of molecular biology - 7 Jul 1995

Veschambre P, Simard P, Jalinot P

Abstract excerpt

Tat strongly activates transcription of the HIV-1 provirus by stimulating both initiation and elongation. This transactivator binds to the TAR RNA element, but can also associate with cellular transcription factors, interacting with upstream promoter sequences. To achieve a better understanding o...

Topics

DNA-Binding Proteins
Fungal Proteins
Gene Expression
Gene Products, tat
Globins
HIV-1
HeLa Cells
Humans
Mutation
Promoter Regions, Genetic
Recombinant Fusion Proteins
Saccharomyces cerevisiae Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

TATA Box

TATA-Box Binding Protein

Transcription Factor TFIIB

Transcription Factors

Transcriptional Activation

tat Gene Products, Human Immunodeficiency Virus

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Open in PubMed

Identifiers

PMID: 7608968
DOI: 10.1006/jmbi.1995.0368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7608968-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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