Article
Heme binding proteins of Bartonella henselae are required when undergoing oxidative stress during cell and flea invasion.
PloS one - 1 Jan 2012
Liu MaFeng, Ferrandez Yann, Bouhsira Emilie, Monteil Martine, Franc Michel, Boulouis Henri-Jean, Biville Francis
Abstract excerpt
Bartonella are hemotropic bacteria responsible for emerging zoonoses. These heme auxotroph alphaproteobacteria must import heme for their growth, since they cannot synthesize it. To import exogenous heme, Bartonella genomes encode for a complete heme uptake system enabling transportation of this compound into the cytoplasm and degrading it to release iron. In addition, these bacteria encode for four or five outer...
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