Article
The heme-binding lipoprotein (HbpA) of Haemophilus influenzae: role in heme utilization.
FEMS microbiology letters - 15 Dec 2005
Morton Daniel J, Madore Larissa L, Smith Ann, Vanwagoner Timothy M, Seale Thomas W, Whitby Paul W, Stull Terrence L
Abstract excerpt
Haemophilus influenzae has an absolute growth requirement for heme and a heme binding lipoprotein (HbpA) has been implicated in the utilization of this essential nutrient. HbpA was identified by examining clones from an H. influenzae genomic library that caused Escherichia coli harboring the clone to bind heme. However, HbpA has not been shown to mediate heme acquisition in H. influenzae. We constructed an...
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