Article
Role of the Haemophilus ducreyi Ton system in internalization of heme from hemoglobin.
Infection and immunity - 1 Jan 1998
Elkins C, Totten P A, Olsen B, Thomas C E
Abstract excerpt
By cloning into Escherichia coli and construction of isogenic mutants of Haemophilus ducreyi, we showed that the hemoglobin receptor (HgbA) is TonB dependent. An E. coli hemA tonB mutant expressing H. ducreyi hgbA grew on low levels of hemoglobin as a source of heme only when an intact H. ducreyi Ton system plasmid was present. In contrast, growth on heme by the E. coli hemA tonB mutant expressing hgbA was...
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