Hemin Binding Protein C Is Found in Outer Membrane Vesicles and Protects Bartonella henselae against Toxic Concentrations of Hemin

Abstract excerpt

Bartonella species are gram-negative, emerging bacterial pathogens found in two distinct environments. In the gut of the obligately hematophagous arthropod vector, bartonellae are exposed to concentrations of heme that are toxic to other bacteria. In the bloodstream of the mammalian host, access to heme and iron is severely restricted. Bartonellae have unusually high requirements for heme, which is their only...

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