Article
Two-locus involvement in the association of human leukocyte antigen with the extrahepatic manifestations of autoimmune chronic active hepatitis.
Hepatology (Baltimore, Md.) - 1 Jun 1994
Marcos Y, Fainboim H A, Capucchio M, Findor J, Daruich J, Reyes B, Pando M, Theiler G C, Méndez N, Satz M L
Abstract excerpt
We investigated the association of human leukocyte antigen antigens and type 1 chronic active "autoimmune" hepatitis in a population of 65 white Argentinian patients, taking into account the different manifestations of the disease. Standard microlymphocytotoxicity was used for human leukocyte antigen A, B, C, DR and DQ typing. Human leukocyte antigen class 2 alleles were also typed on genomic DNA by means of...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Argentina
- Autoimmune Diseases
- Chi-Square Distribution
- Female
- Follow-Up Studies
- Gene Frequency
- Genetic Predisposition to Disease
