Article
Molecular evaluation of HBV core gene mutations in asymptomatic HBV infected blood donors in Iran.
Archives of Iranian medicine - 1 Nov 2014
Ghabeshi Soad, Baktashi Ruhollah, Hosseini Seyed Masoud, Sharifi Zohreh
Abstract excerpt
Mutations in the core promoter and precore regions of HBV cause down-regulation of HBeAg. These mutations are associated with chronic hepatitis, cirrhosis and Hepato Cellular Carcinoma (HCC). This study was carried out to sequence analysis of HBV core gene in HBsAg- positive blood donors in Iran. A total of 50 HBsAg- positive blood donor samples were examined in this study. Serological markers of hepatitis B...
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