Article
Lp(a) catabolism in hypercholesterolaemic individuals.
Chemistry and physics of lipids - 1 Jan 1994
Knight B L
Abstract excerpt
Three pieces of evidence are presented that suggest that LDL receptors are not greatly involved in the catabolism of intact Lp(a) in vivo. First, studies of normal and heterozygous familial hypercholesterolaemic (FH) siblings who have inherited identical apo(a) alleles have shown that the absence...
Topics
- Alleles
- Apolipoproteins
- Apolipoproteins B
- Apoprotein(a)
- Binding, Competitive
- Female
- Heterozygote
- Humans
- Hyperlipoproteinemia Type II
- In Vitro Techniques
- Lipoprotein(a)
- Lipoproteins, LDL
- Male
- Mutation
- Pedigree
- Receptors, LDL