Low density lipoprotein kinetics in a family having defective low density lipoprotein receptors in which hypercholesterolemia is suppressed.

doi:10.1161/01.atv.11.3.578

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Article

Low density lipoprotein kinetics in a family having defective low density lipoprotein receptors in which hypercholesterolemia is suppressed.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000

Vega G L, Hobbs H H, Grundy S M

Abstract excerpt

Heterozygous familial hypercholesterolemia (FH) usually presents with severe elevations of low density lipoprotein (LDL) cholesterol. Recently, a family with FH was described in which several members heterozygous for a mutation in the LDL receptor gene had normal LDL cholesterol levels. Kinetic s...

Topics

Adolescent
Adult
Child
Cholesterol
Female
Heterozygote
Homozygote
Humans
Hyperlipoproteinemia Type II
Kinetics
Lipoproteins, LDL
Male
Mutation
Pedigree
Receptors, LDL

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