Variation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) production.

doi:10.1172/JCI116221

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Article

Variation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) production.

The Journal of clinical investigation - 1 Feb 1993

Rader D J, Cain W, Zech L A, Usher D, Brewer H B

Abstract excerpt

Lipoprotein(a) [Lp(a)] is an atherogenic lipoprotein which is similar in structure to, but metabolically distinct from, LDL. Factors regulating plasma concentrations of Lp(a) are poorly understood. Apo(a), the protein that distinguishes Lp(a) from LDL, is highly polymorphic, and apo(a) size is in...

Topics

Adult
Apolipoproteins
Apoprotein(a)
Female
Humans
Lipoprotein(a)
Male
Phenotype

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