Article
Heparan sulfate proteoglycans are primarily responsible for the maintenance of enzyme activity, binding, and degradation of lipoprotein lipase in Chinese hamster ovary cells.
The Journal of biological chemistry - 13 Oct 1995
Berryman D E, Bensadoun A
Abstract excerpt
Various aspects of lipoprotein lipase (LPL) metabolism, including cell surface binding, degradation, and enzymatic activity, were compared between Chinese hamster ovary (CHO) cells and two distinct proteoglycan-deficient CHO cell lines. The contribution of low density lipoprotein receptor-related...
Topics
- Animals
- CHO Cells
- Cell Membrane
- Clone Cells
- Cricetinae
- Fluorescent Antibody Technique
- Genetic Variation
- Glutathione Transferase
- Heparin
- Kinetics
- Lipoprotein Lipase
- Low Density Lipoprotein Receptor-Related Protein-1
- Proteoglycans
- Receptors, Immunologic
- Receptors, LDL
- Recombinant Proteins
- Transfection