Article
VLDL and IDL apolipoprotein B-100 kinetics in familial hypercholesterolemia due to impaired LDL receptor function or to defective apolipoprotein B-100.
Journal of lipid research - 1 Feb 1998
Zulewski H, Ninnis R, Miserez A R, Baumstark M W, Keller U
Abstract excerpt
Mutations in the apolipoprotein (apo) B, E (LDL) receptor gene and in the apolipoprotein B-100 gene are the cause of familial hypercholesterolemia (FH) and of familial defective apo B-100 (FDB), respectively. Whether these abnormalities lead to altered production or uptake of very low density lip...
Topics
- Adult
- Apolipoprotein B-100
- Apolipoproteins B
- Cholesterol, LDL
- Female
- Humans
- Hyperlipoproteinemia Type II
- Kinetics
- Lipoproteins
- Lipoproteins, IDL
- Lipoproteins, VLDL
- Male
- Middle Aged
- Mutation
- Receptors, LDL
- Triglycerides