HLA-DQA1*0101 haplotypes and disease outcome in early onset pauciarticular juvenile rheumatoid arthritis.

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Article

HLA-DQA1*0101 haplotypes and disease outcome in early onset pauciarticular juvenile rheumatoid arthritis.

The Journal of rheumatology - 1 Jun 1991

van Kerckhove C, Luyrink L, Taylor J, Melin-Aldana H, Balakrishnan K, Maksymowych W, Elma M, Lovell D, Choi E, Glass D N

Abstract excerpt

To further investigate a clinical impression that patients with early onset pauciarticular juvenile rheumatoid arthritis (EOPA-JRA) who carry HLA-DQw1 have more severe arthritis, we subtyped HLA-DQw1 in American midwestern patients with EOPA-JRA. The HLA-DQA1*0101 subtype was present in 10 of 19...

Topics

Alleles
Amino Acid Sequence
Arthritis, Juvenile
Base Sequence
DNA
HLA-DQ Antigens
HLA-DQ alpha-Chains
Haplotypes
Humans
Molecular Sequence Data
Phenotype
Polymorphism, Restriction Fragment Length
Prognosis

Source

Open in PubMed

Identifiers

PMID: 1680192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1680192-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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