Article
Age-specific effects of juvenile rheumatoid arthritis-associated HLA alleles.
Arthritis and rheumatism - 1 Sept 1999
Murray K J, Moroldo M B, Donnelly P, Prahalad S, Passo M H, Giannini E H, Glass D N
Abstract excerpt
OBJECTIVE: To define the onset and duration of effect of the HLA alleles that are associated with disease susceptibility and protection in juvenile rheumatoid arthritis (JRA) and 2 of its subtypes. METHODS: We typed 680 patients with JRA and 254 ethnically matched unrelated controls for HLA class I and II genes. The frequency of each allele was calculated for each of the age-at-onset, onset type, and sex...
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