Article
Nonhereditary p53 mutations in T-cell acute lymphoblastic leukemia are associated with the relapse phase.
Blood - 15 May 1994
Hsiao M H, Yu A L, Yeargin J, Ku D, Haas M
Abstract excerpt
We have previously reported that greater than 60% of human leukemic T-cell lines possess mutations in the p53 tumor suppressor gene. To determine whether T-cell acute lymphoblastic leukemia (T-ALL) patient samples possess p53 mutations, we screened peripheral blood-and bone marrow-derived leukemia samples, taken at diagnosis and at relapse, for p53 mutations. Exons 4 through 9 and selected intron regions of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
