Article
Identification of two homologous antigenic peptides derived from L1 HPV-16 and 18 proteins specific for the HLA-B*3901 allele.
Archives of virology - 1 Oct 2002
Monroy-García A, Weiss-Steider B, Hernández-Montes J, Ortiz-Navarrete V F, Bañuelos-Pánuco A, Acosta-Araujo A, Díaz-Quiñónez A, López-Graniel C M, Herbert G, Granados J, de Leo C, Silva-López R M, Mora-García M L
Abstract excerpt
In this work we present evidence that the homologous peptides IHSMNSTIL and IHSMNSSIL derived from L1 HPV-16 and 18 proteins respectively, and with high specificity for the allele HLA-B*3901, according with an algorithm prediction program, induced T cell stimulation in patients with advanced cervical cancer positive for HPV-16 or 18 infection and for the HLA-B*3901 allele. Interestingly, T lymphocytes derived...
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