Article
Purification of viruses and macromolecular assemblies for structural investigations using a novel ion exchange method.
Virology - 15 May 1994
Walin L, Tuma R, Thomas G J, Bamford D H
Abstract excerpt
We describe a novel ion exchange chromatographic technique suitable for large-scale preparation of viruses and other biomacromolecular assemblies in highly purified form. The method, which utilizes anion exchange on either of two commercially available cellulose cartridges, is applied to the Escherichia coli bacteriophage PRD1. Viral particles eluted from both QMA and DEAE cartridges retain infectivity and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
