Article

The method utilized to purify the SARS-CoV-2 N protein can affect its molecular properties

2021-05-04

Abstract excerpt

One of the main structural proteins of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the nucleocapsid protein (N). The basic function of this protein is to bind genomic RNA and to form a protective nucleocapsid in the mature virion. The intrinsic ability of the N protein to interact with nucleic acids makes its purification very challenging. Therefore, typically employed purification methods appe...

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Literature Corpus work: 0d626420-2c34-599f-8973-cd35312e2b5a
DOI: 10.1101/2021.05.03.442392

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