Article
Confirmation of genetic heterogeneity in familial psoriasis.
Journal of medical genetics - 1 Jul 1995
Matthews D, Fry L, Powles A, Weissenbach J, Williamson R
Abstract excerpt
Psoriasis affects approximately 2% of the European population and is often familial. Linkage of a subset of psoriasis families to loci on chromosome 17q has recently been reported. We have studied members of a large multiply affected family from the north east of England and analysed genotypes for markers from 17q, including the polymorphic microsatellite markers AFM210xa5, AFM163yg1, AFM044xg3, AFMa353yg1, and...
Topics
- Chromosomes, Human, Pair 17
- Female
- Genetic Heterogeneity
- Genetic Markers
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Lod Score
- Male
- Microsatellite Repeats
- Pedigree