Article
Autoantibodies and genetic factors associated with the development of type 1 (insulin-dependent) diabetes mellitus in first degree relatives of diabetic patients.
Diabetologia - 1 Mar 1991
Thivolet C, Beaufrère B, Geburher L, Chatelain P, Orgiazzi J, François R
Abstract excerpt
Factors associated with diabetes onset were analysed for their predictive value in 708 first-degree relatives of Type 1 (insulin-dependent) diabetic patients including 374 parents and 308 siblings of Type 1 diabetic patients. Relatives were prospectively followed for 2,304 subject years with bloo...
Topics
- Adolescent
- Adult
- Alleles
- Autoantibodies
- Child
- Diabetes Mellitus, Type 1
- Family
- Female
- Glucose Tolerance Test
- HLA-DR Antigens
- Haploidy
- Humans
- Insulin Antibodies
- Islets of Langerhans
- Male
- Risk Factors