Article
Analysis of HPV-positive and -negative vulvar carcinomas for alterations in c-myc, Ha-, Ki-, and N-ras genes.
Gynecologic oncology - 1 Apr 1994
Tate J E, Mutter G L, Prasad C J, Berkowitz R, Goodman H, Crum C P
Abstract excerpt
Mutation or overexpression of certain host genes, including c-myc, Ha-ras, and Ki-ras, have been associated with genital squamous neoplasia, specifically in the cervix, and have been implicated in the natural history of these tumors. The relationship of these host gene alterations to vulvar squamous cell carcinomas has not been previously studied. We analyzed archival material from 13 human...
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