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Article

Ki-ras oncogene mutations in non-HPV-associated anal carcinoma.

The Journal of pathology - 1 Jun 1990

Hiorns L R, Scholefield J H, Palmer J G, Shepherd N A, Kerr I B

Abstract excerpt

Human papillomavirus 16 (HPV 16) DNA is found in a high proportion of anal squamous cell carcinomas in whose genesis it is thought to play an important role. In addition, it can be shown to cooperate in vitro with activated ras oncogenes in cellular transformation. We have therefore screened a series of such tumours for activating mutations of the ras oncogene family using DNA amplified in vitro by the polymerase...

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Identifiers

PMID: 2199641
DOI: 10.1002/path.1711610203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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