p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.

doi:10.1006/gyno.1998.5194

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Article

p53 mutations and presence of HPV DNA do not correlate with radiosensitivity of gynecological cancer cell lines.

Gynecologic oncology - 1 Dec 1998

Rantanen V, Grénman S, Kurvinen K, Hietanen S, Raitanen M, Syrjänen S

Abstract excerpt

OBJECTIVE: The correlation between p53 tumor suppressor gene mutations and the presence of high-risk human papillomavirus (HPV) DNA with the in vitro radiosensitivity of gynecological malignancies was studied in 26 cell lines derived from gynecological cancers of 23 patients. METHODS: Comparison...

Topics

DNA, Viral
Female
Genes, p53
Genital Neoplasms, Female
Humans
Mutation
Papillomaviridae
Radiation Tolerance
Tumor Cells, Cultured

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