Article
The emerging picture of p53.
The International journal of biochemistry - 1 Feb 1994
Selter H, Montenarh M
Abstract excerpt
1. The cellular phosphoprotein p53 is a negative regulator of the cell growth. A great majority of human malignancies expresses a mutated p53 that represents an oncogenic version of the protein. 2. However, in the meantime many tumors were identified containing a p53 protein without any mutation....
Topics
- Animals
- Cell Cycle
- Genes, p53
- Genome, Human
- Humans
- Mutation
- Subcellular Fractions
- Tumor Suppressor Protein p53
- Viral Proteins
