Article
Relationship between benzo(a)pyrene-DNA adducts and somatic mutation and recombination in Drosophila melanogaster.
Environmental and molecular mutagenesis - 1 Jan 1994
Zordan M, Osti M, Pavanello S, Costa R, Levis A G
Abstract excerpt
The evaluation of the relationship between the dose to DNA of a mutagen/carcinogen and in vivo somatic cell mutagenesis may provide information on the mechanisms leading to induced mutational events. This can be achieved, for example, by coupling test systems that permit the detection of somatic...
Topics
- Animals
- Benzo(a)pyrene
- Carcinogens
- DNA
- DNA Damage
- DNA Mutational Analysis
- DNA Repair
- Dose-Response Relationship, Drug
- Drosophila melanogaster
- Female
- Genetic Markers
- Larva
- Linear Models
- Male
- Mutagenesis
- Mutagenicity Tests
- Phenotype
- Phosphorus Radioisotopes