Article
Genotoxic effect of the antitumour agent homo-aza-steroidal ester of p-bis-(2-chloroethyl)aminophenoxy acetic acid (NSC 294859) tested in the Drosophila wing somatic mutation and recombination test.
Mutagenesis - 1 Jul 1991
Stephanou G, Demopoulos N A, Catsoulacos P
Abstract excerpt
The genotoxic activity of the new antineoplastic alkylating agent 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17- lactam-p-bis-(2-chloroethyl) aminophenoxyacetate (NSC 294859) was studied in the somatic mutation and recombination test (SMART) in Drosophila melanogaster. T...
Topics
- Animals
- Antineoplastic Agents
- Drosophila melanogaster
- Female
- Genetic Markers
- Male
- Mutagenicity Tests
- Mutagens
- Mutation
- Nitrogen Mustard Compounds
- Recombination, Genetic
- Wings, Animal