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The Wing-Spot and the Comet Tests as Useful Assays Detecting Genotoxicity in Drosophila.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Marcos Ricard, Carmona Erico R

Abstract excerpt

Despite its pioneering use in detecting mutational processes, Drosophila still plays a vital role in studies aimed at detecting and quantifying the induction of DNA damage. Here, we describe two assays: one detecting primary damage (the Comet assay) and the other detecting somatic mutation and recombination effects (the wing-spot test). It is essential to emphasize that somatic recombination is a key event in...

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PMID: 41273697
DOI: 10.1007/978-1-0716-4976-3_22

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