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Article

Evaluation of the genotoxicity of cisplatin, paclitaxel and 5-fluorouracil combined treatment in the Drosophila wing-spot test.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Nov 2010

Danesi Cristiane Cademartori, Bellagamba Bruno Corrêa, Dihl Rafael Rodrigues, de Andrade Heloísa Helena Rodrigues, Cunha Kênya Silva, Lehmann Mauricio

Abstract excerpt

The somatic mutation and recombination test in Drosophila melanogaster was applied to analyze the mutagenic and recombinagenic activity of the chemotherapeutic drugs cisplatin, paclitaxel, and 5-fluorouracil, comparing the effects observed in combinatory treatments with those observed in single a...

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Identifiers

PMID: 20727378
DOI: 10.1016/j.fct.2010.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20727378-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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