Article
Protection by coffee against somatic genotoxicity in Drosophila: role of bioactivation capacity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jan 1996
Abraham S K, Graf U
Abstract excerpt
The protective effects of coffee against somatic mutation and mitotic recombination induced by cyclophosphamide (CPH), mitomycin C (MMC) and urethane (URE) were evaluated in the standard (ST) and high bioactivation (HB) crosses of the wing spot test in Drosophila melanogaster. These two crosses a...
Topics
- Animals
- Coffee
- Cyclophosphamide
- Cytochrome P-450 Enzyme System
- Dose-Response Relationship, Drug
- Drosophila melanogaster
- Female
- Food-Drug Interactions
- Male
- Mitomycin
- Mitosis
- Mutagens
