Article
Protection by coffee against somatic genotoxicity in Drosophila: role of bioactivation capacity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jan 1996
Abraham S K, Graf U
Abstract excerpt
The protective effects of coffee against somatic mutation and mitotic recombination induced by cyclophosphamide (CPH), mitomycin C (MMC) and urethane (URE) were evaluated in the standard (ST) and high bioactivation (HB) crosses of the wing spot test in Drosophila melanogaster. These two crosses are characterized by different constitutive levels of cytochrome )-450-dependent enzyme activities. 3-day old larvae...
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